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Study Shows Effectiveness of Masimo PVIMasimo has reported that a new independent and objective clinical study demonstrated the ability of Pleth Variability Index (PVI) to accurately and noninvasively detect changes in ventricular preload. PVI—the newest addition to the Masimo Rainbow SET technology platform—is a continuous and noninvasive quantified measurement of changes in the perfusion index, capturing volume changes that may compromise cardiac function and affect systemic circulation. Appropriate fluid levels are vital to reducing postoperative risks and improving patient outcomes. The study, entitled “New Algorithm for Automatic Estimation of the Respiratory Variations in the Pulse Oximeter Waveform,” was conducted at the Louis Pradel Hospital in Lyon, France, by a research team headed by Maxime Cannesson, MD. Researchers stated that this study is the “first to demonstrate the ability of PVI, an index automatically derived from the pulse oximeter waveform analysis, to detect changes in ventricular preload. This new index has potential clinical applications for noninvasive hypovolemia detection and fluid responsiveness monitoring.”1 Reference: 1. New Algorithm for Automatic Estimation of the Respiratory Variations in the Pulse Oximeter Waveform. Maxime Cannesson, MD; Bertrand Delannoy, MD; Antoine Morand, MD; Olivier Bastien, MD, PhD; Jean-Jacques Lehot, MD, PhD Anesthesiology, Hospices Civils de Lyon, from Louis Pradel Hospital, Lyon, France. 
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